The first report of the international research consortium organized to map gene-based sequence tagged site markers is now available on the web as an integrated gene map. The human genome is thought to harbor 50,000 to 100,000 genes, of which about half have been sampled to date in the form of expressed sequence tags. More than 16,000 human genes have been mapped relative to a framework map that...
The purpose of this moderated newsgroup is to provide a proper forum for the discussion of issues pertaining to and involving genome and/or chromatin structure and function. Primarily it should enable those researchers who work in genome/chromatin structure or related fields to communicate ideas and information, as well as provide a chance for collaboration among national and international...
On April 6, Celera Genomics announced that it had completed the sequencing phase of one person's genome. It will now begin the process of assembling the sequenced fragments into their proper order with the aid of powerful computers. Work on this project began in September 1999 using a method called "whole genome shotgun sequencing," a quicker method than that used by the international Human Genome...
One key aspect of genetics research is associating variations in gene sequences with heritable phenotypes. To that end, the NCBI (National Center for Biotechnology Information) has released the database of human genetic variation (dbSNP), containing "both the experimental conditions used to find each mutation and each mutation's observed variation for populations and individuals."
The National Center for Biotechnology Information of the National Library of Medicine (part of the National Institutes of Health) has just posted a new gene of the Human Genome (first described in the October 25, 1996 Scout Report), showing the positions, associated data and annotations for more than 30,000 human gene-based markers. Produced "by a collaboration of 63 scientists from government,...
Over the last few weeks, scientists announced they have completed mapping Chromosome 21, the chromosome associated with Down's syndrome, epilepsy, Lou Gehrig's disease, and Alzheimer's. Researchers hope the achievement will lead to treatments in the future. Nature Magazine, features a free page, Genome Gateway, with online original research papers from Nature and Nature Genetics relating to...
Scientists announced Wednesday that they had deciphered chromosome 20, the largest of the three chromosomes to be sequenced thus far. Researchers hope that this latest advance by the Human Genome Project will help explain why some people are more susceptible to diseases such as diabetes or obesity. Also the gene that seems to make some a higher risk for Cruetzfeldt--Jakob Disease, the human...
This no-frills UC-Santa Cruz Genome Bioinformatics Web site contains searchable "working drafts of the human genome and the mouse genome," which each represent "immense collaborative efforts" within the biomedical research community. Those who are active in genome research may find this Web site useful, especially for the multi-faceted genome browser that "provides a rapid and reliable display of...
In an effort to track the progress of and provide access to the work of the Human Genome Project (see the October 14, 1998 Scout Report for Science & Engineering), the National Center for Biotechnology Information (NCBI) of the National Library of Medicine (NLM) has expanded their Web resource. An international research program "designed to construct detailed genetic and physical maps of the human...
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